Terfenadine therapy: can we justify the risks?
نویسنده
چکیده
DEPUIS LA MISE EN VENTE DE LA TERFÉNADINE, antihistaminique non sédatif, il y a plus de 20 ans, des rapports sur des cas d’arythmie cardiaque et de mort subite associée à son utilisation ont entraîné son retrait du marché dans certains pays. Néanmoins, la terfénadine est toujours en vente au Canada. Les avantages qu’offre ce médicament pour contrôler les symptômes de la fièvre des foins ne l’emportent sûrement pas sur les risques d’effets indésirables qui peuvent être mortels. De plus, la disponibilité continue de ce médicament est injustifiée compte tenu des solutions de rechange sans danger qui existent.
منابع مشابه
SERIOUS ARRHYTHMIA INDUCED BY TERFENADINE-ERYTHROMYCIN INTERACTIONS
Since the introduction of our local manufacturing of terfenadine, we have observed and expressed our concern about a small but increasing number of serious ventricular arrhythmias associated with the use of this non sedating antihistamine. In January 1997 a case of torsade de pointes ventricular tachycardia was detected in a previously healthy woman taking terfenadine with erythromycin. El...
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ورودعنوان ژورنال:
- CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
دوره 157 1 شماره
صفحات -
تاریخ انتشار 1997